A. Sloan Devlin

The paper identifies gut bacteria-produced metabolites that inhibit HSD11B2, altering cortisol signaling and linking microbiome activity to blood pressure regulation.

The paper identifies lithocholic acid as a bile acid metabolite that modulates circadian rhythms in intestinal cells by affecting core clock proteins and feedback loops.

This study shows that the vitamin D receptor is essential for metabolic health after sleeve gastrectomy in mice, affecting insulin sensitivity, white adipose tissue function, and inflammation, with similar findings in human patients.

The paper isolates bacteria from PSC patient bile and shows they induce inflammation and cell death in human cells.