Author

Fabrizio Chiti

University of FlorenceORCID 0000-0002-1330-1289Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Alessandra BigiiD· 1 shared Alfonso De SimoneiD· 1 shared Andrea DananiiD· 1 shared Anna Rosa CartaiD· 1 shared Annalisa Brivio· 1 shared Augusta PisanuiD· 1 shared Clara PorceddaiD· 1 shared Cristina CecchiiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperBiochemistry

Alessandra BigiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintMar 30, 2026

Corticospinal propagation of full-length TDP-43 toxicity drives brain-to-muscle pathology

Jacopo Marongiu, V. Crippa, Isabella Marzi…·Anna Rosa Carta

This study shows that full-length TDP-43 spreads from the brain to muscle in rats, causing pathology and dysfunction.

DOI 10.64898/2026.03.27.714692

𝕏 PostBluesky

BiochemistryCommunications BiologyPeer-reviewedMar 27, 2026

Engineering a Dimeric Single-Domain Antibody for Improved Detection and neutralization of Amyloid-β oligomers

Liliana Napolitano, Devkee M. Vadukul, Alessandra Bigi…·Francesco A. Aprile

This study engineers a dimeric single-domain antibody that improves detection and neutralization of amyloid-β oligomers, showing enhanced specificity and efficacy compared to its monomeric form.

1 citation

humanproteomics

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BiophysicsbioRxivPreprintJan 31, 2024

Leveraging Machine Learning-Guided Molecular Simulations Coupled with Experimental Data to Decipher Membrane Binding Mechanisms of Aminosterols

Stefano Muscat, Silvia Errico, Andrea Danani…·Gianvito Grasso

This paper uses machine learning and simulations to study how aminosterols bind to neuron-like membranes, showing accurate predictions matching experimental data.

DOI 10.1101/2024.01.31.578042

deep learningprotein folding & dynamics

𝕏 PostBluesky