Author

Ravesanker Ezhilarasan

NYU Langone HealthORCID 0000-0002-1353-8307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Aram Sandaldjian ModrekiD· 2 shared Catherine DoiD· 2 shared Erik P. SulmaniD· 2 shared Giulia CovaiD· 2 shared Jane A. SkokiD· 2 shared Jerome M. KarpiD· 2 shared Yingwen DingiD· 2 shared Ze-Yan ZhangiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersGenomics

Aram Sandaldjian ModrekORCID

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2 papers

Recent·Most cited

Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma

Aram Sandaldjian Modrek, Keerthivasan Raanin Chandradoss, Catherine Do, Ravesanker Ezhilarasan, Theodore Sakellaropoulos, Jerome M. Karp, Yingwen Ding, Ze-Yan Zhang, Maria L. G. Quiloan, Melanie Graciani, Giulia Cova, Jennifer E. Phillips‐Cremins, Erik P. Sulman, Jane A. Skok

This study shows that DNA damage in glioblastoma cells leads to long-term chromatin changes and gene expression reprogramming, affecting cellular function and tumor outcomes.

Nature Communications · Aug 29, 2026Peer-reviewedGenomics

mtgRNA-db: An annotated database of multi-target CRISPR-Cas9 guide-RNAs in the human genome

Aram Sandaldjian Modrek, Khoi Huynh, Catherine Do, Jerome M. Karp, Yingwen Ding, Ze-Yan Zhang, Ravesanker Ezhilarasan, Belen Valor, Giulia Cova, Jane A. Skok, Erik P. Sulman

The paper creates a database of multi-target CRISPR-Cas9 guide-RNAs with on- and off-target scores and provides a web tool for selecting these guide-RNAs.

bioRxiv · May 7, 2025 · PreprintBioinformatics