Caroline Isaac

This study identifies ribosome biogenesis as a therapeutic vulnerability in TNBC, showing that inhibiting rRNA maturation via Fibrillarin or RNA Pol I reduces tumor growth without significant cell death.

This study identifies RSL24D1 as a key regulator of ribosome biogenesis and pluripotency in mouse embryonic stem cells, showing its role in maintaining self-renewal and suppressing differentiation.

This study develops a deep learning algorithm for analyzing label-free brightfield microscopy images to detect cancer stem-like cell fate, showing improved accuracy and speed compared to other methods.