Author

Piero Lo Monaco

Lyon 1 UniversitéORCID 0000-0002-5365-4126Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Angéline Gaucherot· 2 shared Camille Jouines· 2 shared Frédéric CateziD· 2 shared Jean‐Jacques DiaziD· 2 shared Marie‐Ambre MonetiD· 2 shared Virginie MarceliD· 2 shared Carine FromentiD· 1 shared Caroline IsaaciD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Angéline Gaucherot

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2 papers

Recent·Most cited

Cancer BiologyBreast Cancer ResearchPeer-reviewedNov 13, 2025

Fibrillarin-mediated ribosomal RNA maturation is a novel therapeutic vulnerability in triple-negative breast cancer

Camille Jouines, Piero Lo Monaco, Angéline Gaucherot…·Frédéric Catez

This study identifies ribosome biogenesis as a therapeutic vulnerability in TNBC, showing that inhibiting rRNA maturation via Fibrillarin or RNA Pol I reduces tumor growth without significant cell death.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintMar 26, 2025

Ribosome biogenesis is a therapeutic vulnerability in paediatric neuroblastoma

Camille Jouines, Piero Lo Monaco, Angéline Gaucherot…·Frédéric Catez

This study investigates ribosome biogenesis as a therapeutic target in neuroblastoma, showing that inhibiting RNA polymerase I reduces cell proliferation and induces apoptosis.

DOI 10.1101/2025.03.26.645392

humanbulk RNA-seq

𝕏 PostBluesky