BioengineeringbioRxivPreprint
Precursor of chemically expanded hepatocytes (pre-cHep) with 1-million-fold expansion potential and liver repopulation capacity
Linh Huynh, Yuichiro Higuchi, Cherie Tsz‐Yiu Law…·Keisuke Kaji
The paper reports a method to reprogram primary human hepatocytes into proliferative pre-cHep cells with high expansion potential and liver repopulation capacity, offering an alternative to PHHs for drug testing and disease modeling.
DOI 10.64898/2026.05.15.725446