Naser Ansari‐Pour

Sequential acquisition of 1p31.1-p12 LOH and 1q Gain is a common double-hit event in relapsed/refractory myeloma

The paper identifies a therapy-driven genomic double-hit (1pCEN LOH and 1q gain) in relapsed/refractory myeloma, associated with poor prognosis and clonal expansion.

Whole-genome analysis of Nigerian patients with breast cancer reveals ethnic-driven somatic evolution and distinct genomic subtypes

The paper analyzes whole-genome data from Nigerian breast cancer patients, identifying ethnic-driven somatic evolution and distinct genomic subtypes associated with African ancestry.

Multi-site clonality analyses uncovers pervasive subclonal heterogeneity and branching evolution across melanoma metastases

The paper analyzes whole-genome sequencing data from melanoma metastases to show that branched evolution is common and that subclonal heterogeneity is prevalent in metastatic melanoma.

Can we assume the gene expression profile as a proxy for signaling network activity?

This study evaluates whether gene expression profiles can reliably infer signaling network activity and finds they are not more coherent with causal relationships than random data.

A Logic-Based Dynamic Modeling Approach to Explicate the Evolution of the Central Dogma of Molecular Biology

This paper modifies and mathematically models the Central Dogma of molecular biology using Boolean networks to show increased complexity and robustness in biological systems.

The genetic legacy of Zoroastrianism in Iran and India: Insights into population structure, gene flow and selection.

This study analyzes genetic data from Zoroastrians in Iran and India to explore population structure, gene flow, and selection, revealing patterns of endogamy, admixture timing, and disease-related selection.