Author

Oliver Till Keppler

German Center for Infection ResearchORCID 0000-0002-1384-8946Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adrian RuhleiD· 1 shared Hong‐Ru CheniD· 1 shared Hsiu-Hui YangiD· 1 shared Javier M. VillamizariD· 1 shared Madeleine GappiD· 1 shared Manuel AlbaneseiD· 1 shared Nicole P. KadziochiD· 1 shared Niklas Arndt SchmackeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Adrian RuhleORCID

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1 paper

Recent·Most cited

Optimizing CRISPR/Cas9 genome editing in primary human hematopoietic cells to advance studies into HIV biology

Hong‐Ru Chen, Nicole P. Kadzioch, Madeleine Gapp, Hsiu-Hui Yang, Adrian Ruhle, Javier M. Villamizar, Thimo Fuchs, Niklas Arndt Schmacke, Veit Hornung, Roberto F. Speck, Oliver Till Keppler, Manuel Albanese

This study develops a CRISPR/Cas9 platform for editing primary human HSPCs to investigate HIV host factors and their impact on viral infection in vitro and in vivo.

bioRxiv · Aug 5, 2026 · PreprintBioengineering