Author

Nicole P. Kadzioch

University of ZurichORCID 0000-0002-0432-8658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Roberto F. SpeckiD· 2 shared Adrian RuhleiD· 1 shared Ana Alcaraz‐SernaiD· 1 shared Cloé BrennaiD· 1 shared Constantinos PetrovasiD· 1 shared Craig W. FenwickiD· 1 shared Duy-Cat CaniD· 1 shared Francesco A. Procopio· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

Roberto F. SpeckORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Optimizing CRISPR/Cas9 genome editing in primary human hematopoietic cells to advance studies into HIV biology

Hong‐Ru Chen, Nicole P. Kadzioch, Madeleine Gapp, Hsiu-Hui Yang, Adrian Ruhle, Javier M. Villamizar, Thimo Fuchs, Niklas Arndt Schmacke, Veit Hornung, Roberto F. Speck, Oliver Till Keppler, Manuel Albanese

This study develops a CRISPR/Cas9 platform for editing primary human HSPCs to investigate HIV host factors and their impact on viral infection in vitro and in vivo.

bioRxiv · Aug 5, 2026 · PreprintBioengineering

Targeting PD-1+ T-cells with Chimeric Antigen Receptors to reduce the HIV Reservoir

Laura Ermellino, Riddhima Banga, Spiros Georgakis, Nicole P. Kadzioch, Francesco A. Procopio, Ana Alcaraz‐Serna, Oscar Alfageme-Abello, Raphaël Porret, Rebecca Cecchin, Michail Orfanakis, Rachel Schelling, Cloé Brenna, Duy-Cat Can, Mathilde Foglierini, Oliver Y. Chén, , Yannick D. Müller

This study designs PD-1-targeting CAR-T-cells to reduce the HIV reservoir by depleting specific T-cell subpopulations in HIV-infected humanized mice.

Science Advances · Apr 24, 2026Peer-reviewedImmunology