Liuh Ling Goh

Polygenic Risk Scores Across Genomic Platforms for Reliable Breast Cancer Risk Stratification

This paper evaluates differences in a breast cancer polygenic risk score across genomic platforms and finds that calibration improves consistency in high-risk classification.

Nuclear regulatory disturbances precede and predict the development of Type-2 diabetes in Asian populations

The paper identifies DNA methylation biomarkers predictive of Type-2 diabetes in Asian populations and shows their utility in risk stratification.

RAPTOR: A Five-Safes approach to a secure, cloud native and serverless genomics data repository

RAPTOR provides a secure, cloud-native genomics repository with a five-safes framework to ensure compliance and data protection for genomic research.

Large-scale whole-genome sequencing of three diverse Asian populations in Singapore

This study presents whole-genome sequencing data from 4,810 Singaporeans across three ethnic groups, revealing genetic structure, admixture, and improved imputation for Asian and Oceanian populations.