Author

Ariana Ghez Farrell

Fred Hutch Cancer CenterORCID 0000-0002-1389-0992Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Organism:human· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Jesse D. BloomiD· 2 shared Aaron J. SchmitziD· 1 shared Ali H. EllebedyiD· 1 shared Anders MadseniD· 1 shared Annie M. DoseyiD· 1 shared Benjamin S. StrnadiD· 1 shared Bernadeta DadonaiteiD· 1 shared Caroline KikawaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Jesse D. BloomORCID

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2 papers

Recent·Most cited

Defining the molecular interaction between influenza hemagglutinin and MHC-II

Bernadeta Dadonaite, Annie M. Dosey, Jenny J. Ahn, Timothy C. Yu, Sara Sunshine, Ariana Ghez Farrell, Neil P. King, Jesse D. Bloom

The paper identifies molecular interactions between influenza HAs and MHC-II, showing avian MHC-II enables more efficient entry than human MHC-II for most H5 HAs and reveals structural and functional similarities across different HA subtypes.

bioRxiv · Jul 22, 2026 · PreprintMicrobiology

mRNA-based influenza vaccine expands breadth of B cell response in humans

Hanover C. Matz, Tae-Geun Yu, Kritika Dixit, Caroline Kikawa, Julian Q. Zhou, Garazi Peña Alzua, Lowrey Peyton, Anders Madsen, Fangjie Han, Ariana Ghez Farrell, Robert Hoelzl, Aaron J. Schmitz, Stephen C. Horvath, Hunter K. Keplinger, Benjamin S. Strnad, , Ali H. Ellebedy

An mRNA-based influenza vaccine induces broader and more durable B cell responses compared to inactivated influenza virus vaccine in humans.

Nature Immunology · Jun 15, 2026Peer-reviewedImmunology