Author
Washington University in St. LouisORCID 0000-0002-8077-6751Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Adam M. Chazin-Gray, Tuscan Rock Thompson, Edward D. B. Lopatto…·David A. Baker
This study designs miniprotein inhibitors targeting bacterial adhesins to prevent and treat urinary tract infections.
Hanover C. Matz, Tae-Geun Yu, Kritika Dixit…·Ali H. Ellebedy
An mRNA-based influenza vaccine induces broader and more durable B cell responses compared to inactivated influenza virus vaccine in humans.
Sameer Kumar Malladi, Deepika Jaiswal, Baoling Ying…·Ali H. Ellebedy
Booster SARS-CoV-2 mRNA vaccine recruits and broadens GC B cell responses targeting a highly conserved site on receptor binding domain of spike glycoprotein.
Edward D. B. Lopatto, Jesús M. Santiago-Borges, Denise A. Sanick…·Scott J. Hultgren
This study identifies two monoclonal antibodies against FimH adhesin that protect mice from E. coli UTI by sterically blocking FimH function, offering an antibiotic-sparing treatment strategy.
Zachary T. Berndsen, Marjahan Akhtar, Mahima Thapa…·James M. Fleckenstein
This study identifies key structural and glycosylation features of EtpA, an ETEC adhesin, and shows how antibodies target different epitopes to influence immune responses and pathogen-host interactions.