Author

Touraj Aligholipour Farzani

Broad InstituteORCID 0000-0002-1392-4048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Approach:deep learning· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

Al OzonoffiD· 2 shared Christina F. SpiropoulouiD· 2 shared Clarice Borges· 2 shared Éric BergeroniD· 2 shared Jessica R. SpengleriD· 2 shared Lisa E. HensleyiD· 2 shared Nallely EspinozaiD· 2 shared Pardis Christine SabetiiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Al OzonoffORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

A Low Containment CCHFV Entry Screening Platform Identifies Compounds with Antiviral Activity against Authentic CCHFV

Nallely Espinoza, Sophie N. Spector, Jessica R. Harmon, Payel Chatterjee, Markus H. Kainulainen, Mike Flint, Clarice Borges, Mahdis Manafi, Tsion Abay, Jessica R. Spengler, Éric Bergeron, Christina F. Spiropoulou, Lisa E. Hensley, Al Ozonoff, Touraj Aligholipour Farzani, Pardis Christine Sabeti

This study identifies eltrombopag olamine and quercetin as CCHFV entry inhibitors using a BSL-2 pseudotype screening platform validated against authentic CCHFV under BSL-4 conditions.

bioRxiv · Aug 30, 2026 · PreprintMicrobiology

Modular mRNA LNP design integrates RNA, lipid, and antigen engineering for protective vaccination

Touraj Aligholipour Farzani, Nallely Espinoza, Mahdiyeh M. Manafi, Stephen R. Welch, JoAnn D. Coleman-McCray, Virginia Aida-Ficken, Jessica R. Spengler, Éric Bergeron, Christina F. Spiropoulou, Clarice Borges, Kristine Bielecki, Lee Li, Devan Shah, Marietou Faye Paye, Eugenia Rojas, , Pardis Christine Sabeti

This paper designs an mRNA-LNP vaccine by integrating RNA, lipid, and antigen engineering to achieve 90% protection in a murine model.

bioRxiv · Jan 18, 2026 · PreprintMicrobiology