Author

Jan Vrbský

International Clinical Research Center, St. Anne's University Hospital BrnoORCID 0000-0002-1406-2929Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel Pereira-SousaiD· 2 shared Giancarlo ForteiD· 2 shared Marco CassaniiD· 2 shared Sofia MorazzoiD· 2 shared Soraia FernandesiD· 2 shared Filip KafkaiD· 1 shared Francesco NiroiD· 1 shared Frank CarusoiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Daniel Pereira-SousaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

ERK3/MAPK6 promotes triple-negative breast cancer progression through collective migration and EMT plasticity

Sofia Morazzo, Soraia Fernandes, Marina Fortea, Helena Skálová, Daniel Pereira-Sousa, Marco Cassani, Kamila Vrzalová, Filip Kafka, Jan Vrbský, Mathilde Soulez, Sylvain Meloche, Ole Morten Seternes, Veronika Bosáková, Jaeyoung Shin, Jan Frič, , Giancarlo Forte

This study shows ERK3 promotes TNBC progression through EMT plasticity and collective migration, linking it to poor clinical outcomes.

Frontiers in Oncology · Aug 27, 2025Peer-reviewedCancer Biology

Regulation of cell-nanoparticle interactions through mechanobiology

Marco Cassani, Francesco Niro, Soraia Fernandes, Daniel Pereira-Sousa, Sofia Morazzo, Helena Ďuríková, Tianzheng Wang, Lara González‐Cabaleiro, Jan Vrbský, Jorge Oliver‐De La Cruz, Šimon Klimovič, Jan Přibyl, Tomáš Loja, Petr Skládal, Frank Caruso, Giancarlo Forte

This study shows that inhibiting the Hippo pathway component yes-associated protein increases nanoparticle internalization in cancer cells, independent of nanoparticle or cell properties.

Nano Letters · Jan 8, 2025Peer-reviewedBioengineering