Author

Paul Schnacke

ETH ZurichORCID 0000-0002-1419-5895Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:protein folding & dynamics· 2 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

Julian van GerweniD· 2 shared Kathrin LangiD· 2 shared Maximilian FottneriD· 2 shared Pedro BeltrãoiD· 2 shared Andrea C. Carrano· 1 shared Andrew R. JonesiD· 1 shared Bede P. BusbyiD· 1 shared Denys A. KvashaiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersCell Biology

Julian van GerwenORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 8, 2025

Mapping the functional importance of site-specific ubiquitination across the human proteome

Julian van Gerwen, Maximilian Fottner, Shengbo Wang…·Pedro Beltrão

The paper maps the functional importance of site-specific ubiquitination across the human proteome by analyzing conservation, perturbation, and machine learning scores.

3 citations

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintSep 22, 2025

Repurposing UBE2W for programmable protein ubiquitylation

Paul Schnacke, Maximilian Fottner, Julian van Gerwen…·Kathrin Lang

This paper introduces UbyW, a platform for site-specific ubiquitylation using UBE2W, enabling efficient production of ubiquitylated proteins and identifying USP15 as a deubiquitylase for Ran K71 monoubiquitylation.

1 citation

E. coliprotein sequence

𝕏 PostBluesky