Clément Léna

The paper shows that vlPAG/DRN and FN neurons coordinate activity during fear learning in mice, supporting their functional interaction in threat prediction.

This study identifies two cerebello-thalamic pathways in mice with distinct roles in motor skill learning and consolidation.

This study shows that offline reactivations in a brain-wide motor circuit predict motor strategy exploration during rest and retention through cerebellar sleep spindles and functional connectivity.

This paper develops an inertial sensor-based method to decompose rodent behavior into elementary components using unsupervised segmentation and clustering, achieving detailed behavioral mapping and detecting motor changes in Parkinson's disease models.

The paper identifies a hindbrain neuron cluster, Sup5Phox2b, essential for coordinating biting and chewing during feeding.

A mouse model of DYT25 dystonia with a Gnal mutation shows altered cerebello-thalamic plasticity, which can be modulated by theta-burst stimulation to reduce dystonia severity.

The paper shows microglial TNFα regulates GABAAR plasticity, sleep slow waves, and memory consolidation through purinergic signaling.

The paper shows that cerebellar stimulations reduce or prevent levodopa-induced dyskinesia in mice by normalizing brain activity and reversing neuronal plasticity.

This study shows the cerebellum controls fear memory strength via the ventrolateral periaqueductal grey through glutamatergic projections, with a separate pathway influencing anxiety and fear expression.

This study identifies two cerebellar-thalamic pathways with distinct roles in motor learning and offline consolidation in mice.

The paper shows that caudal cerebellar vermis cells re-encode head movements into a gravity-polarized representation.