Romain W Sala

Multiple Functions of Cerebello-Thalamic Neurons in Learning and Offline Consolidation of a Motor Skill in mice.

This study identifies two cerebello-thalamic pathways in mice with distinct roles in motor skill learning and consolidation.

Offline cerebello-cortico-striatal dynamics predict motor strategy exploration and retention in skill learning

This study shows that offline reactivations in a brain-wide motor circuit predict motor strategy exploration during rest and retention through cerebellar sleep spindles and functional connectivity.

Functional abnormalities in the cerebello-thalamic pathways in an animal model of dystonia

A mouse model of DYT25 dystonia with a Gnal mutation shows altered cerebello-thalamic plasticity, which can be modulated by theta-burst stimulation to reduce dystonia severity.

Microglial TNFα controls GABAAR plasticity, sleep slow waves and memory consolidation

The paper shows microglial TNFα regulates GABAAR plasticity, sleep slow waves, and memory consolidation through purinergic signaling.

Activity-dependent modulation of NMDA receptors by endogenous zinc shapes dendritic function in cortical neurons.

The paper shows that vesicular zinc modulates NMDA receptor activity in cortical neurons, affecting dendritic function and synaptic plasticity under in vivo-like conditions.

Bidirectional control of fear memories by the cerebellum through the ventrolateral periaqueductal grey

This study shows the cerebellum controls fear memory strength via the ventrolateral periaqueductal grey through glutamatergic projections, with a separate pathway influencing anxiety and fear expression.

Dual contributions of cerebellar-thalamic networks to learning and offline consolidation of a complex motor task.

This study identifies two cerebellar-thalamic pathways with distinct roles in motor learning and offline consolidation in mice.