Author

Madhan Mohan Chandra Sekhar Jaggarapu

Case Western Reserve UniversityORCID 0000-0002-1437-6311Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Abhinav P. AcharyaiD· 2 shared Abhirami ThumsiiD· 2 shared Sanmoy Pathak· 2 shared Abhirami Suresh· 1 shared Abigail Raffner BassoniD· 1 shared Bo ZhangiD· 1 shared Carlo De SalvoiD· 1 shared Drishtant SinghiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Abhinav P. AcharyaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 7, 2026

Mesaconic acid delivery via biomaterials and engineered probiotics to the gut reduces inflammation in Crohn's Diseases mouse models

Huikang Qian, Drishtant Singh, Zixuan Chen…·Abhinav P. Acharya

The paper develops two strategies to increase mesaconate levels in the gut to reduce inflammation in Crohn's Disease mouse models.

DOI 10.64898/2026.10.01.756006

mouseexperimental assay

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BioengineeringbioRxivPreprintJan 12, 2026

Polymer of methyl malonic acid suppress inflammation by downregulating IL-2 through ROS overproduction

Sanmoy Pathak, Madhan Mohan Chandra Sekhar Jaggarapu, Taravat Khodaei…·Abhinav P. Acharya

This paper develops a polymer, 1,6 MMA, that suppresses inflammation by reducing IL-2 and increasing mitochondrial ROS in T cells, showing therapeutic potential in collagen-induced arthritis.

DOI 10.64898/2026.01.11.698915

𝕏 PostBluesky