Author

Thibault Vantieghem

Leiden University Medical CenterORCID 0000-0002-1452-9584Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Ananya MukundaniD· 1 shared Andrew P. HinckiD· 1 shared Caroline S. HilliD· 1 shared Cynthia S. HinckiD· 1 shared Łukasz WieteskaiD· 1 shared Maarten van DintheriD· 1 shared Peter ten DijkeiD· 1 shared Rick M. MaizelsiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBioengineering

Ananya MukundanORCID

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1 paper

Recent·Most cited

BioengineeringbioRxivPreprintMar 24, 2026

Pro-domain-dependent folding and co-receptor-mediated targeting to optimize an antagonistic TGF-β monomer for gene-based delivery

Łukasz Wieteska, Cynthia S. Hinck, Ananya Mukundan…·Andrew P. Hinck

This paper improves the folding and targeting of an engineered TGF-β monomer for gene-based delivery by modifying its pro-domain and adding a CD44 binding domain.

DOI 10.64898/2026.03.23.713733

humanprotein structure

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