A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes
François Kroll, Gareth T. Powell, Marcus Ghosh, Gaia Gestri, Paride Antinucci, Timothy J. Hearn, Hande Tunbak, Sumi Lim, Harvey W Dennis, Joseph M. Fernandez, David Whitmore, Elena Dreosti, Stephen W. Wilson, Ellen J. Hoffman, Jason Rihel
This paper introduces a CRISPR-Cas9 method for rapid generation of F0 biallelic knockouts in zebrafish, enabling quick screening of complex phenotypes.
eLife · Jan 8, 2021Peer-reviewedGenetics