John F. Baines

This study evaluates 42 new Bacteroidota strains for probiotic potential, finding they inhibit biofilm formation and exhibit quorum quenching and bile salt hydrolase activity.

This study examines how gut bacteria genomes adapt to industrialization, finding convergent genomic responses in stress response, cell envelope remodeling, and central metabolism across different populations.

This study investigates long-term intestinal epithelial changes after acute protein-energy malnutrition using multi-omics approaches and identifies microbial lipid metabolites and epigenetic factors as key drivers of persistent Paneth cell dysfunction.

This study shows gut microbiota influences disease severity in an experimental pemphigoid model, with specific taxa linked to protection or inflammation.

The paper integrates multi-omics data from mice to identify molecular features linked to aging-related cognitive decline, highlighting systemic inflammation and microbiome-driven gut-brain axis dysfunction.

This study tracks rapid genetic diversification of Bacteroides thetaiotaomicron in mono-associated mice over 28 days, identifying polymorphisms, phase-variable loci, and spatial variation in the gut.

This study uses multi-omics and metabolic modeling in mice to show that aging reduces host-microbiome metabolic interactions, affecting key host pathways involved in intestinal barrier function and homeostasis.

The paper uses genetic mapping in hybrid mice to show host genetics shape gut microbiome traits, identifies 443 loci influencing 123 taxa, and finds disease-related genes.

This study shows that high mitochondrial heteroplasmy in mice reduces lifespan and impairs glucose metabolism.