Douglas A. Coulter

This study shows that retuning ventral hippocampal output in TLE mice improves social memory and reduces anxiety without suppressing seizures.

The paper shows that increasing dentate granule cell excitability using chemogenetics causes seizures and spatial memory deficits in non-epileptic mice, supporting the dentate gate hypothesis.

The paper investigates how prolonged hyperactivity in hippocampal neurons leads to persistent chloride ion accumulation in a subset of cells using imaging and statistical analysis.