Pei Hao

This study investigates antibiotic resistance genes and bacteria in hadal trench sediments using cultivation and metagenomics, finding a pristine reservoir with distinct ARG dynamics and phylogenetic clusters.

The paper introduces DENA, a neural network model trained on Nanopore sequencing data to detect and quantify N6-methyladenosine (m6A) in RNA, showing high accuracy in Arabidopsis and consistency with human data.

This study compares transcriptomes from SARS-CoV-2, SARS-CoV, and MERS-CoV infections to investigate alternative entry routes and innate immune responses.

The paper implements and repurposes the CRISPR-Cas13a system in fission yeast for precise RNA editing, demonstrating reduced off-target effects and programmable nucleotide editing.