Hongbing Wang

The paper calculates ribosome protein stoichiometry ratios across tissues and developmental stages, revealing functional ribosome heterogeneity in health and disease.

The paper shows that dopamine-induced postsynaptic bursts enable input-specific LTP in hippocampal synapses, enhancing associative plasticity of temporally discontiguous inputs.

This study shows that vorinostat improves cognitive and non-cognitive symptoms in a mouse model of fragile X syndrome without affecting abnormal protein synthesis.

This study shows that carbamazepine improves cognitive and behavioral deficits in a mouse model of fragile X syndrome by reducing ERK[1/2] and Akt signaling and protein synthesis.

The paper identifies trifluoperazine as a potential treatment for FXS using transcriptome analysis and experimental validation.

The paper implements and repurposes the CRISPR-Cas13a system in fission yeast for precise RNA editing, demonstrating reduced off-target effects and programmable nucleotide editing.