H3.3 deposition counteracts the replication-dependent enrichment of H3.1 at chromocenters in embryonic stem cells
Stefano Arfè, Tina Karagyozova, Audrey Forest, Dominic Bingham, Hatem Hmidan, David Mazaud, Mickaël Garnier, Patricia Le Baccon, Eran Meshorer, Jean‐Pierre Quivy, Geneviève Almouzni
The paper shows H3.3 deposition counteracts H3.1 enrichment at chromocenters in ESCs, affecting heterochromatin stability and cell survival.
Nature Communications · Jun 3, 2025Peer-reviewedCell Biology