Author

Harry M. T. Choi

California Institute of TechnologyORCID 0000-0002-1530-0773Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:spatial domain detection· 3 Research Focus:cell-cell communication· 2 Assay:spatial transcriptomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Niles A. PierceiD· 3 shared Maayan SchwarzkopfiD· 2 shared Alexandre CunhaiD· 1 shared Aneesh AcharyaiD· 1 shared Georgios Artavanis· 1 shared Johannes StegmaieriD· 1 shared Mark E. FornaceiD· 1 shared Mike C. LiuiD· 1 shared

Activity by Year

2018-2021 · peak 2/yr

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10 top collaborators · 30 mutual co-author links

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3 shared papersDevelopmental Biology

Niles A. PierceORCID

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3 papers

Recent·Most cited

Hybridization chain reaction enables a unified approach to multiplexed, quantitative, high-resolution immunohistochemistry and in situ hybridization

Maayan Schwarzkopf, Mike C. Liu, Samuel J. Schulte, Rachel Ives, N. Husain, Harry M. T. Choi, Niles A. Pierce

This paper introduces a method using hybridization chain reaction for multiplexed, quantitative, high-resolution imaging of both proteins and RNA in challenging tissues.

Development · Nov 15, 2021Peer-reviewedDevelopmental Biology

Third-generation in situ hybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust

Harry M. T. Choi, Maayan Schwarzkopf, Mark E. Fornace, Aneesh Acharya, Georgios Artavanis, Johannes Stegmaier, Alexandre Cunha, Niles A. Pierce

This paper introduces third-generation in situ HCR with automatic background suppression, enabling multiplexed, quantitative mRNA imaging and flow cytometry with improved performance and ease-of-use.

Development · Jun 15, 2018Peer-reviewedDevelopmental Biology

Multidimensional quantitative analysis of mRNA expression within intact vertebrate embryos

Vikas Trivedi, Harry M. T. Choi, Scott E. Fraser, Niles A. Pierce

This paper introduces a method to quantitatively analyze mRNA expression in whole vertebrate embryos with subcellular resolution, enabling both anatomical to expression and expression to anatomical queries.

Development · Jan 1, 2018Peer-reviewedDevelopmental Biology