Piotr J. Balwierz

The paper creates a central repository for zebrafish developmental genomics data, identifies new cis-regulatory elements, and compares regulatory elements between zebrafish and mouse.

The paper identifies genes regulated by retinoic acid signaling in zebrafish endoderm using RNA-seq, ChIP-seq, and ATAC-seq, and finds conserved RAR binding sites across vertebrates.

The paper shows zebrafish primordial germ cells use germ plasm in two phases to regulate transcriptome divergence from somatic cells through post-transcriptional mechanisms and chromatin changes.

The paper identifies dual-initiation promoters in zebrafish that use both canonical and non-canonical initiation motifs, showing differential regulation during development and conservation across species.