Ana Rosa López-Pérez

Single-Cell Cross-Species Profiling identifies Conserved Transcriptional Networks in Early Pancreatic Tumourigenesis.

The paper uses cross-species single-cell RNA-seq to identify conserved transcriptional networks in early pancreatic tumourigenesis across zebrafish, mouse, and human.

Bone Marrow Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling

This study uses spatial transcriptomics to analyze bone marrow in MM mouse models and patients, revealing altered T-cell distribution, neutrophil traps, and inflammatory signaling in MM.

GeneSetCluster 2.0: a comprehensive toolset for summarizing and integrating gene-sets analysis

GeneSetCluster 2.0 improves gene-set analysis by reducing redundancies, enhancing computational efficiency, and providing accessible tools for both programmers and non-programmers.

AMPK-activator ATX-304 reduces oxidative stress and improves MASLD via metabolic switching

This study shows that ATX-304, an AMPK activator, reduces oxidative stress and improves MASLD in mice by altering liver metabolism and lipid distribution.

Identification of downstream effectors of retinoic acid specifying the zebrafish pancreas by integrative genomics.

The paper identifies genes regulated by retinoic acid signaling in zebrafish endoderm using RNA-seq, ChIP-seq, and ATAC-seq, and finds conserved RAR binding sites across vertebrates.