Rubayet Elahi

This study identifies essential enzymes in the pyrimidine biosynthesis pathway of Plasmodium falciparum and demonstrates their critical roles in parasite survival.

The paper investigates whether reduced PfPSS expression affects resistance of PfATP4 mutant parasites to antimalarials, finding no significant change in drug efficacy.

The paper identifies multiple redundant carboxylic acid transporters in Plasmodium falciparum that support mitochondrial metabolism, revealing metabolic flexibility in the parasite.

This paper identifies and characterizes TilS in the apicoplast of Plasmodium falciparum, showing its essential role in tRNA lysidinylation and parasite survival.

This study identifies MnmE and MnmG as essential enzymes for xm5s2U modification in Plasmodium falciparum apicoplast tRNAs, revealing a minimal biosynthetic pathway critical for apicoplast maintenance.