Krithika Rajaram

This study identifies essential enzymes in the pyrimidine biosynthesis pathway of Plasmodium falciparum and demonstrates their critical roles in parasite survival.

The paper investigates whether reduced PfPSS expression affects resistance of PfATP4 mutant parasites to antimalarials, finding no significant change in drug efficacy.

This paper identifies PfAnchor as an essential protein for apicoplast fission and inheritance in Plasmodium falciparum, showing its interaction with PfDyn2 and its role in parasite survival.

The paper identifies multiple redundant carboxylic acid transporters in Plasmodium falciparum that support mitochondrial metabolism, revealing metabolic flexibility in the parasite.

The paper redesigns a TetR-aptamer system to improve stability and efficiency in controlling gene expression in Plasmodium falciparum.