Harriet E. Allan

Hepatic Xanthine Oxidoreductase Sustains Antithrombotic Nitric Oxide Signalling Through the Nitrate-Nitrite-Nitric Oxide Pathway

This study shows that hepatic xanthine oxidoreductase (XOR) sustains antithrombotic nitric oxide signaling through the nitrate-nitrite-NO pathway, and dietary nitrate can restore this signaling when endothelial NO is deficient.

Megakaryocyte activation and mobilization from the bone marrow in response to trauma and hemorrhagic shock in mice

This study shows trauma and hemorrhagic shock rapidly alter megakaryocyte activity and mobilization in mice within one hour.

Platelet mitochondrial transfer via extracellular vesicles modulates neutrophil phenotype and function

This study shows that platelet extracellular vesicles containing mitochondria are internalized by neutrophils, altering their activation, adhesion, migration, and phagocytic capacity.