Author

Chan Wu

University of Massachusetts Chan Medical SchoolORCID 0000-0002-1570-3345Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 3 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 4 Organism:yeast· 4 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Assay:metagenomics· 2 Assay:bulk RNA-seq· 1 Assay:multiome· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Allan JacobsoniD· 4 shared Feng HeiD· 4 shared Alper CelikiD· 1 shared Bijoyita RoyiD· 1 shared Kotchaphorn MangkalaphibaniD· 1 shared Richard Baker· 1 shared Robin GanesaniD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMolecular Biology

Allan JacobsonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Dcp2 C-terminal Cis-Binding Elements Control Selective Targeting of the Decapping Enzyme by Forming Distinct Decapping Complexes

Feng He, Chan Wu, Allan Jacobson

The paper identifies cis-binding elements in Dcp2 that form distinct decapping complexes, controlling mRNA targeting specificity in yeast.

eLife · May 23, 2022Peer-reviewedMolecular Biology

Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae

Kotchaphorn Mangkalaphiban, Feng He, Robin Ganesan, Chan Wu, Richard Baker, Allan Jacobson

The paper investigates stop codon readthrough in yeast using ribosome profiling and bioinformatics to identify mRNA features influencing termination efficiency.

PLoS Genetics · Apr 20, 2021Peer-reviewedGenetics

Nonsense suppression position effect implicates poly(A)-binding protein in the regulation of translation termination

Chan Wu, Bijoyita Roy, Feng He, Allan Jacobson

The paper investigates how the position of nonsense codons affects readthrough efficiency in yeast, showing that poly(A)-binding protein regulates translation termination.

bioRxiv · Oct 6, 2019 · PreprintMolecular Biology

General decapping activators target different subsets of inefficiently translated mRNAs

Feng He, Alper Celik, Chan Wu, Allan Jacobson

The paper identifies that decapping activators target specific subsets of inefficiently translated mRNAs and reveal the role of the Dcp2 C-terminal domain in both positive and negative regulation.

eLife · Dec 6, 2018Peer-reviewedMolecular Biology