Michael J. Hall

This study shows YME1L1 is not essential for T cell activation despite its upregulation and role in mitochondrial structure.

The paper shows melanin-containing phagosomes in keratinocytes mature into storage lysosomes called melanokerasomes, which retain melanin for long-term photoprotection.

The paper identifies deacidification of distal lysosomes in aged neurons as a mechanism driving synapse loss and shows that restoring acidification can reverse synaptic decline.