Bertrand Cariou

This study shows that the LIPC-E97G variant enhances the cholesterol-lowering and anti-atherogenic effects of evinacumab in Ldlr-/- mice.

This study identifies ACSF3 as a diurnal regulator of lysine-malonylation and hepatic metabolism, showing its rhythmic expression and role in glycogen storage, lipogenesis, and triglyceride synthesis.

This study shows that Seipin regulates tripartite ER-mitochondria-lipid droplet contact sites, which are critical for adipocyte lipid storage and metabolic flexibility.

This study shows that extracellular vesicles with surface-anchored adiponectin improve insulin sensitivity and reduce obesity-related metabolic issues in mice.

This study identifies a shared molecular signature in adipose tissue dysfunction across obesity and lipodystrophy, revealing common metabolic pathways and genetic loci associated with type 2 diabetes.

KILDA identifies KIV-2 repeats and Lp(a)-affecting variants from kmers, achieving results comparable to DRAGEN-LPA on the 1000 Genomes Project.