Xavier Prieur

This study shows that Seipin regulates tripartite ER-mitochondria-lipid droplet contact sites, which are critical for adipocyte lipid storage and metabolic flexibility.

This study shows that timing DHODH inhibition during dawn reduces obesity in male mice by improving mitochondrial function and metabolic rhythms.

This study shows that extracellular vesicles with surface-anchored adiponectin improve insulin sensitivity and reduce obesity-related metabolic issues in mice.

This study identifies a shared molecular signature in adipose tissue dysfunction across obesity and lipodystrophy, revealing common metabolic pathways and genetic loci associated with type 2 diabetes.

This study shows that seipin regulates CAV1 trafficking and organelle interactions by controlling lipid metabolism and membrane order, impacting cellular homeostasis and metabolic disorders.