Molecular BiologyCell GenomicsPeer-reviewed
Ribonuclease activity undermines immune sensing of naked extracellular RNA
Mauricio Castellano, Valentina Blanco, Marco Li Calzi…·Juan Pablo Tosar
This study shows that naked extracellular RNA can be pro-inflammatory and functionally active in immune cells when ribonuclease inhibitors are present, challenging the need for RNA encapsulation.
12 citations