Author

Mercedes Segovia

Universidad de la República de UruguayORCID 0000-0002-1641-1985Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:metagenomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alfonso CayotaiD· 1 shared Bruno CostaiD· 1 shared Juan Pablo TosariD· 1 shared Kenneth Whitaker WitweriD· 1 shared Marcelo HilliD· 1 shared Marco Li CalziiD· 1 shared Mauricio CastellanoiD· 1 shared Valentina BlancoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Alfonso CayotaORCID

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1 paper

Recent·Most cited

Ribonuclease activity undermines immune sensing of naked extracellular RNA

Mauricio Castellano, Valentina Blanco, Marco Li Calzi, Bruno Costa, Kenneth Whitaker Witwer, Marcelo Hill, Alfonso Cayota, Mercedes Segovia, Juan Pablo Tosar

This study shows that naked extracellular RNA can be pro-inflammatory and functionally active in immune cells when ribonuclease inhibitors are present, challenging the need for RNA encapsulation.

Cell Genomics · May 1, 2025Peer-reviewedMolecular Biology