Pamela M. Maras

This paper performs a meta-analysis of gene expression data from five datasets to identify long-term effects of early life stress on the prefrontal cortex, finding consistent downregulation of myelin-related genes and upregulation of genes related to Major Depressive Disorder.

This study shows that adolescent environmental enrichment improves social resilience and alters gene expression in genetically anxious rats, with differential effects on behavior and stress response.

This study identifies genetic loci associated with exploratory locomotion and anxiety-like traits in a selectively bred rat model using a genome-wide association approach.

The paper investigates how microglia morphology differs between rat lines with distinct emotional temperaments and links these differences to baseline microglial reactivity.

The paper characterizes behavioral, physiological, and neuroendocrine profiles of mice before, during, and after chronic social defeat stress, finding that early coping strategies better predict resilience or susceptibility than traditional behavioral read-outs.

This study identifies gene expression differences in the hippocampus of selectively-bred rats associated with internalizing and externalizing behaviors across development and adulthood.

Blocking CRH receptor type 1 in adulthood mitigates age-related memory impairments caused by early-life adversity in rats, but not all memory functions.