Author

Meghan S. Vermillion

Lovelace Medical CenterORCID 0000-0002-1602-7027Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:non-human primate· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Arya VijjapurapuiD· 2 shared Dustin S. SiegeliD· 2 shared Jared PittsiD· 2 shared Jason K. PerryiD· 2 shared John P. BilelloiD· 2 shared Nicholas C. RiolaiD· 2 shared Raju SubramanianiD· 2 shared Richard L. MackmaniD· 2 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Arya VijjapurapuORCID

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Author profile →

2 papers

Recent·Most cited

Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeys

Jared Pitts, J. Lizbeth Reyes Zamora, Savrina Manhas, Thomas Aeschbacher, Josolyn Chan, Vincent Cutillas, Varsha Nair, Nicholas C. Riola, Arya Vijjapurapu, Meghan S. Vermillion, Stacey Eng, Christopher M. Richards, Dong Han, Jason K. Perry, Subhra Chaudhuri, , John P. Bilello

This study shows that oral obeldesivir is effective against RSV infection in African green monkeys, reducing viral load significantly.

Nature Communications · Jul 11, 2025Peer-reviewedMicrobiology

Discovery and Synthesis of GS-7682, a Novel Prodrug of a 4'-CN-4-Aza-7,9-Dideazaadenosine C-Nucleoside with Broad-Spectrum Potency Against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.

Dustin S. Siegel, Hon C. Hui, Jared Pitts, Meghan S. Vermillion, Kazuya Ishida, Davin Rautiola, Michael Keeney, Hammad Irshad, Lijun Zhang, Kwon Chun, Gregory Chin, Bindu Goyal, Edward M. Doerffler, Hai Yang, Michael O. Clarke, , Richard L. Mackman

This paper describes the discovery and synthesis of GS-7682, a prodrug with broad antiviral activity against RSV and other viruses, showing efficacy in RSV-infected monkeys.

Journal of Medicinal Chemistry · Jul 17, 2024Peer-reviewedBiochemistry