Joseph T. Bass

NADH dehydrogenase reverses dietary and clock metabolic syndrome

This study shows that circadian disruption impairs metabolic health by causing mitochondrial complex I dysfunction, which affects adipocyte function and metabolic pathways.

A role for the spinal cord cholinergic neuron circadian clock in RNA metabolism and mediating ALS disease phenotypes

The paper shows that the circadian clock in spinal cord cholinergic neurons affects RNA metabolism and contributes to ALS disease phenotypes through rhythmic gene expression and alternative splicing.

Mitofusin 2 controls mitochondrial and synaptic dynamics of suprachiasmatic VIP neurons and related circadian rhythms including sleep

This study shows that mitofusin 2 regulates mitochondrial and synaptic dynamics in SCN VIP neurons, affecting circadian rhythms and sleep in mice.

Cryptochromes-mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism

The paper shows mammalian Cryptochromes inhibit CRL4Cop1 complex assembly, similar to their function in plants, by interacting with Det1 to repress GR transcription.