Colleen R. Reczek

This study shows that circadian disruption impairs metabolic health by causing mitochondrial complex I dysfunction, which affects adipocyte function and metabolic pathways.

This study shows metformin lowers blood glucose by inhibiting intestinal mitochondrial complex I, increasing lactate and GDF15, and promoting glucose uptake.

This study shows that increasing mitochondrial NAD+ regeneration via MitoLbNOX does not rescue dopaminergic neuron dysfunction caused by complex I impairment in Parkinson's disease mice.

This study shows that the circadian clock in muscle stem cells modulates immune responses and inflammation during muscle regeneration through NAD+ metabolism and CCL2 signaling.