The paper identifies Mon1 as a key regulator of oskar mRNA localization and axial patterning in oocytes, showing both cell autonomous and non-cell autonomous roles.

bioRxiv · Dec 25, 2025 · PreprintDevelopmental Biology

Prolonged exposure to insulin causes epigenetic alteration leading to insulin resistance

Shehnaz Bano, Shyam More, Dattatray Mongad, Abdul Khalique, Dhiraj Prakash Dhotre, Manoj Kumar Bhat, Vasudevan Seshadri

The paper shows prolonged insulin exposure without glucose causes epigenetic changes leading to insulin resistance in cells and mice.

bioRxiv · Apr 28, 2022 · PreprintMolecular Biology

A cost-effective and efficient approach for generating and assembling reagents for conducting real-time PCR

Ridim Dadasaheb Mote, V Shinde Laxmikant, Surya Bansi Singh, Mahak Tiwari, Hemant Kumar Singh, J.P. Srivastava, Vidisha Tripathi, Vasudevan Seshadri, Amitabha Majumdar, Deepa Subramanyam

The paper describes a cost-effective method for preparing cDNA synthesis and real-time PCR mastermixes that match commercial kits' efficiency, addressing financial barriers in low-resource settings.

Journal of Biosciences · Nov 27, 2021Peer-reviewedMolecular Biology

Phylogenomic analysis of SARS-CoV-2 genomes from western India reveals unique linked mutations

Dhiraj Paul, Kunal Jani, Janesh Kumar, Radha Chauhan, Vasudevan Seshadri, Girdhari Lal, Rajesh Prabhakar Karyakarte, Suvarna Joshi, Murlidhar Tambe, Sourav Sen, Santosh K. Karade, Kavita Bala Anand, S.P.S. Shergill, Rajiv Mohan Gupta, Manoj Kumar Bhat, , Yogesh Shreepad Shouche

The paper analyzes SARS-CoV-2 genomes from western India, identifying unique linked mutations and their association with symptoms and age groups.

bioRxiv · Jul 30, 2020 · PreprintGenomics