Amitabha Majumdar

Biomolecular condensates of Eya drive transcriptional co-activation associated with eye development

This study identifies Eya biomolecular condensates as transcription hubs in eye development, showing their dynamic state is essential for co-activation and linked to disease.

Pathogenic mutations in Clathrin Heavy Chain associated with intellectual disability impair synaptic architecture and learning in Drosophila

Polyol sugar osmolyte - sorbitol corrects chromosome cohesion and translational defects in cohesin muta

This study shows that sorbitol corrects chromosome cohesion and translational defects in cohesin mutants by reducing ER stress and protein misfolding.

Identification of two novel DnaJ chaperone family proteins as modifiers of Huntingtin aggregates

The paper identifies two DnaJ chaperone proteins, CG5001 and P58IPK, that reduce HTT aggregation in HD models, suggesting their potential as therapeutic targets.

Mrj an Hsp40 family chaperone regulates oligomerization of Orb2 and long-term memory

This study identifies Mrj as a chaperone that regulates Orb2A oligomerization, which is essential for long-term memory maintenance in Drosophila.

A cost-effective and efficient approach for generating and assembling reagents for conducting real-time PCR

The paper describes a cost-effective method for preparing cDNA synthesis and real-time PCR mastermixes that match commercial kits' efficiency, addressing financial barriers in low-resource settings.