Cancer BiologybioRxivPreprint
MtDNA heteroplasmy controls tumor immune reprogramming through mitochondrial translation
Ning Liu, Guoshi Chai, Qunyu Lv…·Shang Cai
The paper shows that mtDNA heteroplasmy regulates tumor progression by modulating mitochondrial translation and immune microenvironment remodeling through the LARS2-S100A8/A9 axis.
DOI 10.64898/2026.01.31.693596