Author

Sydney L. Solomon

Ragon Institute of MGH, MIT and HarvardORCID 0000-0002-1614-1743Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Bianca A. Lepe· 2 shared Bryan D. BrysoniD· 2 shared Benjamin L. AllsupiD· 1 shared Cal Gunnarsson· 1 shared Christine R. Zheng· 1 shared Hattie ChungiD· 1 shared Jacob B. Hochfelder· 1 shared Jeff C. HsiaoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

Bianca A. Lepe

Mutual co-authors in cluster

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJul 22, 2026

Bacterial surface display enables lysis-independent joint host-pathogen single-cell profiling

Cal Gunnarsson, Jeff C. Hsiao, Jacob B. Hochfelder…·Bryan D. Bryson

This paper introduces a lysis-independent method for joint host-pathogen single-cell profiling using bacterial surface display, enabling analysis of both host and pathogen features in infected cells.

DOI 10.64898/2026.07.21.739887

bacteria (other)flow cytometry

𝕏 PostBluesky

MicrobiologyMicrobiology SpectrumPeer-reviewedDec 17, 2024

Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery anddelivery of novel cargoes to the Mtb surface

Bianca A. Lepe, Christine R. Zheng, Owen K. Leddy…·Bryan D. Bryson

This study identifies Mtb outer membrane proteins using protease shaving and mass spectrometry, revealing novel vaccine targets and methods to deliver cargoes to the Mtb surface.

5 citations

proteomicsexperimental assay

𝕏 PostBluesky