Author

Ekaterina L. Andrianova

Genome CanadaORCID 0000-0002-1628-8702Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Bioinformatics· 1 Cancer Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 3 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Andrei V. GudkoviD· 5 shared Anatoli S. GleibermaniD· 2 shared Konstantin AvchacioviD· 2 shared Peter O. FedicheviD· 2 shared Alexandra A. CrookiD· 1 shared Alexandra V. VylegzhaninaiD· 1 shared Alma SolisiD· 1 shared Amelia RoselliiD· 1 shared

Activity by Year

2022-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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5 shared papersImmunology

Andrei V. GudkovORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cancer BiologyBlood Cancer DiscoveryPeer-reviewedJul 17, 2026

The Nicotinamide Salvage Pathway is a Metabolic Vulnerability of High-Risk MDS Stem Cells

Sweta B. Patel, Daniel R Moskop, Steven Moreira…·Eric Martin Pietras

This study identifies NAMPT as a metabolic vulnerability in HR-MDS HSPCs, showing its inhibition reduces their survival and disease burden.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyScience Translational MedicinePeer-reviewedJun 3, 2026

Toll-Like-Receptor 5 protects against pulmonary fibrosis by reducing lung dysbiosis

Yosuke Sakamachi, Emma Wiley, Carol S. Trempus…·Stavros Garantziotis

TLR5 deficiency is linked to pulmonary fibrosis due to its role in preventing microbial dysbiosis following lung injury.

4 citationstop 3%

𝕏 PostBluesky

ImmunologybioRxivPreprintJun 1, 2026

mRNA-Encoded TLR5 Agonist as an Immune Adjuvant

Alexandra V. Vylegzhanina, Oscar Murillo Gomez, Ilya I. Gitlin…·Andrei V. Gudkov

This study tests an mRNA-encoded TLR5 agonist as an adjuvant to enhance mRNA vaccine immunogenicity and efficacy.

DOI 10.64898/2026.05.30.728968

𝕏 PostBluesky

Systems BiologybioRxivPreprintFeb 12, 2026

Thermodynamic scaling of canine aging and reversible clock deceleration by a reverse transcriptase inhibitor

Simon S. Matrenok, Ekaterina L. Andrianova, Konstantin Avchaciov…·Peter O. Fedichev

The paper tracks aging in sled dogs using a variational autoregressive model to show that lamivudine temporarily decelerates DNA methylation clocks but not long-term biological age.

DOI 10.64898/2026.02.10.705136

DNA methylationstatistical model

𝕏 PostBluesky

BioinformaticsNature CommunicationsPeer-reviewedNov 1, 2022

Identification of a blood test-based biomarker of aging through deep learning of aging trajectories in large phenotypic datasets of mice

Konstantin Avchaciov, Marina P. Antoch, Ekaterina L. Andrianova…·Peter O. Fedichev

This paper develops a deep learning model to identify a blood-based biomarker of aging in mice using phenotypic data, finding it correlates with aging hallmarks and predicts lifespan.

36 citations

mousebulk RNA-seq

𝕏 PostBluesky