Author

Sweta B. Patel

University of Colorado AnschutzORCID 0000-0001-7082-7204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

Angelo D’AlessandroiD· 4 shared Ana VujoviciD· 2 shared Austin E. GilleniD· 2 shared Brett M. StevensiD· 2 shared Craig T. JordaniD· 2 shared Daniel StephensoniD· 2 shared Eric Martin PietrasiD· 2 shared Julie A. ReisziD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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4 shared papersCancer Biology

Angelo D’AlessandroORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Maternal Folate Nutrition Programs Adult Hematopoietic Stem Cell Function Through Mitochondrial Remodeling

Brian P Krum, Ava Niazi, Victoria Chiou, Brittant Curtiss, Noah Huerta, Fanny Zhou, Luisa F. Castillo, Sweta B. Patel, Alana Marie Franceski, Sajesan Aryal, Anton Classen, Travis G. Nemkov, Angelo D’Alessandro, Martha S. Field, Rui Lu, , Anna E. Beaudin

This study shows maternal folate levels influence adult hematopoietic stem cell function through mitochondrial and chromatin changes in offspring.

bioRxiv · Oct 28, 2026 · PreprintCell Biology

The Nicotinamide Salvage Pathway is a Metabolic Vulnerability of High-Risk MDS Stem Cells

Sweta B. Patel, Daniel R Moskop, Steven Moreira, Stephanie Gipson, Colin C. Anderson, Alexandra A. Crook, Maxwell C. McCabe, Daniel Stephenson, Hannah E. Terry, Andrew Kent, Tracy N. Young, Anna E. Krug, Connon I. Thomas, Caitlin Price, Monica Ransom, , Eric Martin Pietras

This study identifies NAMPT as a metabolic vulnerability in HR-MDS HSPCs, showing its inhibition reduces their survival and disease burden.

Blood Cancer Discovery · Jul 17, 2026Peer-reviewedCancer Biology

Aberrant oxidative metabolism selects for TET2-deficient hematopoietic stem and progenitor cells

Katia E. Niño, Vera Ademà, Alyx E. Gray, Courtney M Cowan, Wolfgang E. Schleicher, Mohsen Hosseini, Sierra N. Bennett, Sweta B. Patel, Steven Moreira, Etienne P. Danis, Feyiang Ma, Hsin-Ying Lin, Tracy N. Young, Colin A. Anderson, Devyani Sharma, , Eric Martin Pietras

This study shows that aberrant oxidative metabolism drives the selection of TET2-deficient hematopoietic stem and progenitor cells in clonal hematopoiesis, with the pentose phosphate pathway playing a compensatory role.

bioRxiv · Mar 2, 2026 · PreprintCancer Biology

Therapy resistance in AML is mediated by cytoplasmic sequestration of the transcriptional repressor IRF2BP2

Mark Jordan Althoff, Mohd Minhajuddin, Brett M. Stevens, Austin E. Gillen, Stephanie Gipson, Sweta B. Patel, Ian T. Shelton, Regan Miller, Ana Vujovic, Anna Krug, Tracy Young, William M. Showers, Monika Dzieciątkowska, Daniel Stephenson, Anit Tyagi, , Craig T. Jordan

This study identifies IRF2BP2 cytoplasmic sequestration by MCL1 as a mechanism driving venetoclax and azacitidine resistance in AML through ACSL1 derepression.

bioRxiv · May 22, 2025 · PreprintCancer Biology