Author

Eric Martin Pietras

University of Colorado AnschutzORCID 0000-0002-7339-8828Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Angelo D’AlessandroiD· 2 shared Julie A. ReisziD· 2 shared Steven MoreiraiD· 2 shared Sweta B. PateliD· 2 shared Tracy N. YoungiD· 2 shared Alexandra A. CrookiD· 1 shared Alexis Georgiades· 1 shared Ali Toghani· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

Angelo D’AlessandroORCID

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3 papers

Recent·Most cited

The Nicotinamide Salvage Pathway is a Metabolic Vulnerability of High-Risk MDS Stem Cells

Sweta B. Patel, Daniel R Moskop, Steven Moreira, Stephanie Gipson, Colin C. Anderson, Alexandra A. Crook, Maxwell C. McCabe, Daniel Stephenson, Hannah E. Terry, Andrew Kent, Tracy N. Young, Anna E. Krug, Connon I. Thomas, Caitlin Price, Monica Ransom, , Eric Martin Pietras

This study identifies NAMPT as a metabolic vulnerability in HR-MDS HSPCs, showing its inhibition reduces their survival and disease burden.

Blood Cancer Discovery · Jul 17, 2026Peer-reviewedCancer Biology

Aberrant oxidative metabolism selects for TET2-deficient hematopoietic stem and progenitor cells

Katia E. Niño, Vera Ademà, Alyx E. Gray, Courtney M Cowan, Wolfgang E. Schleicher, Mohsen Hosseini, Sierra N. Bennett, Sweta B. Patel, Steven Moreira, Etienne P. Danis, Feyiang Ma, Hsin-Ying Lin, Tracy N. Young, Colin A. Anderson, Devyani Sharma, , Eric Martin Pietras

This study shows that aberrant oxidative metabolism drives the selection of TET2-deficient hematopoietic stem and progenitor cells in clonal hematopoiesis, with the pentose phosphate pathway playing a compensatory role.

bioRxiv · Mar 2, 2026 · PreprintCancer Biology

Semaphorin 4A maintains functional diversity of the hematopoietic stem cell pool

Dorsa Toghani, Sanika Gupte, Sharon Zeng, Elmir Mahammadov, Edie I. Crosse, Negar Seyedhassantehrani, Christian S. Burns, David M. Gravano, Stefan Radtke, Hans‐Peter Kiem, Sonia Rodrı́guez, Nadia Carlesso, Amogh Pradeep, Alexis Georgiades, Fabienne McClanahan Lucas, , Lev Silberstein

This study identifies Sema4A as an extrinsic factor that protects myeloid-biased HSCs from inflammatory stress, preserving functional diversity in the hematopoietic stem cell pool.

Nature Aging · Jan 29, 2025Peer-reviewedCell Biology