Author

Geoffrey A. Smith

Harvard UniversityORCID 0000-0002-1638-4219Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adrienne Margaret FlanaganiD· 1 shared Akhil PampanaiD· 1 shared Alistair G. RustiD· 1 shared Angelo PeloneroiD· 1 shared Arun PadmanabhaniD· 1 shared Brian L. BlackiD· 1 shared Bryan Hill-Fung LauiD· 1 shared Charlotte G ButterworthiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Adrienne Margaret FlanaganORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 4, 2026

Murine osteosarcoma recapitulates the driver landscape and genomic complexity of osteosarcoma evolution in humans

Geoffrey A. Smith, Ianthe A. E. M. van Belzen, Mathieu Epinette…·Tyler Jacks

This study shows that a genetically engineered mouse model of osteosarcoma recapitulates the genomic complexity and driver mutations observed in human osteosarcoma.

1 citation

mousewhole-genome sequencing

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GenomicsScience Translational MedicinePeer-reviewedSep 14, 2022

CSDE1 is a Post-Transcriptional Regulator of the LDL Receptor

Geoffrey A. Smith, Arun Padmanabhan, Bryan Hill-Fung Lau…·John S. Chorba

A genome-wide CRISPR screen identifies CSDE1 as a key regulator of hepatic LDLR mRNA decay in vivo, making it a promising target for heart disease.

25 citationstop 3%

mouseexperimental assay

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