Susana M. D. A. Garcia

This study shows that RNA nucleotide repeats cause mitochondrial dysfunction and ribosome-associated quality control issues in C. elegans, with Coenzyme Q supplementation rescuing the defects.

This study shows that loss of MBL-1 in C. elegans reduces p38 MAPK/PMK-1 and transcription factor activity, shortening lifespan, and suggests mitochondrial stress may alleviate DM1 symptoms.

This study shows that RNA interference in C. elegans mediates RNA toxicity from maternal CTG repeats, causing offspring phenotypes that can be rescued by disrupting the RNAi machinery.